Mild Hyperbaric Oxygen Therapy
Mild Hyperbaric Oxygen Therapy (mHBOT) involves breathing oxygen in a gently pressurized chamber (typically 1.3–1.5 ATA). This increased pressure boosts oxygen absorption not only through red blood cells but also directly into plasma and other body fluids, significantly increasing tissue oxygen levels—by up to 300–600%. This enhanced oxygen delivery supports cellular repair, reduces inflammation, and promotes overall healing and regeneration.
Although hyperbaric oxygen therapy was once believed to be effective only at high pressures (above 1.5 ATA), growing scientific evidence now supports the effectiveness of low-pressure protocols as well.
Dr. Paul Harch, a U.S. specialist with over 30 years of experience treating brain and neurological conditions with HBOT, advocates for low-pressure therapy, especially for the brain. Since the nervous system is highly sensitive, he emphasizes that gentler treatment—using lower pressure—is often more beneficial. In these cases, less is more, as the body needs to manage the increased oxygen load carefully.
Here you can find the studies demonstrating the benefits of low-pressure hyperbaric oxygen therapy.
STUDIES
LOW PRESSURE HAS MORE EFFECT ON GENE EXPRESSION
This study surprisingly reveals that low-pressure therapy (less than 1.5 ATA) had a significantly stronger effect on gene expression compared to high-pressure therapy (2.4 ATA).
10 SESSIONS WITH 1.3ATA PRESSURE INCREASED THE PRODUCTION OF STEM CELLS IN THE BODY 3X!
Recent study from 2023. Until now, high pressure (2.0 ATA) barotherapy with added pure oxygen was known to increase stem cell production 8x after 20 sessions. But it turned out that just 10 sessions with 1.3 ATA pressure and without any supplemental oxygen (just air) increased stem cell production by as much as 3x!
A STUDY COMPARING 3 DIFFERENT PRESSURE PROTOCOLS FOUND NO DIFFERENCE IN OUTCOMES
This study compared protocols with 3 different pressures:
- 1,3 ATA without added oxygen, just air
- 1,5 ATA with added oxygen
- 1,75 ATA with added oxygen
The study was conducted on children with cerebral palsy and they were followed for 8 months. Much to everyone's surprise, there was no difference in the results of the protocols. All of these produced powerful healing. This study changed the way many think about hyperbaric oxygen therapy.
EVEN VERY SMALL CHANGES IN PRESSURE CAUSE SIGNIFICANT CHANGES IN THE BODY
Only in the last 20 years have we begun to investigate more precisely what changes in pressure do to the body, and it has turned out that even small changes in pressure create large physiological effects in the body. By now, it is clear that practically every pressure change between 1.0 ata (air pressure at sea level) and 1.3 ATA falls under hyperbaric oxygen therapy.
Dr. Paul Harch has put together a comprehensive article showing the scientific evidence that even a change in barometric pressure of 1.04 ATA is an effective therapy at the cellular level.
1.6 ATA HAD A SIGNIFICANTLY STRONGER EFFECT ON BRAIN INJURY HEALING COMPARED TO 2.2 ATA
This rat study compared the effects of hyperbaric oxygen chamber on brain damage with different protocols. One group received therapy at 1.6ATA pressure, the other at 2.2ATA. It turned out that the 1,6ATA protocol was significantly more effective in healing brain damage.
HYPERBARIC OXYGEN THERAPY WITHOUT SUPPLEMENTAL OXYGEN AFFECTED GENE EXPRESSION MORE THAN WITH 100% OXYGEN
The study found that hyperbaric oxygen therapy changed the expression of 183 genes, but sessions with air had a significantly stronger effect than sessions with added oxygen. It can be concluded that pressure changes, not oxygen, are the main influencers of gene expression.
MORE RESEARCH PAPERS
Small changes in pressure create significant changes »
Low pressure hyperbaric oxygen therapy in the recovery program of athletes »
Low pressure hyperbaric oxygen chamber helped autistic children »
Low-pressure hyperbaric oxygen chamber lowered blood pressure »
Low pressure hyperbaric oxygen therapy helped with arthritis »
Hyperbaric oxygen therapy for diabetes »
Cognitive deficits resulting from mold improved with hyperbaric oxygen chamber »
Low pressure hyperbaric oxygen therapy helps with muscle injuries »
Autistic children achieved significant results in just 10 sessions at a pressure of 1.3 ATA »
Low pressure hyperbaric oxygen therapy reduces cardiovascular risks »
Full recovery of 2-year-old child from brain injury after almost drowning »
Low pressure hyperbaric oxygen therapy helps with diabetes »
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